Thought Leadership

Executive Order Directs Attorney General to Finalize Cannabis Rescheduling

December 18, 2025 Advisory

President Trump’s Executive Order directs federal agencies to “take all necessary steps to complete the rulemaking process” to reclassify cannabis from Schedule I to Schedule III. This action marks the most significant federal cannabis policy shift in over half a century. The executive order is designed to enable medical research on cannabis, which was otherwise restricted, and provide for significant banking reform in the cannabis industry.

While rescheduling does not legalize cannabis federally, it reflects a significant breakthrough for industry actors and medical researchers.

Research and Banking Implications

Moving cannabis to Schedule III removes many of the restrictive barriers that have long hindered medical and pharmaceutical research in the United States. The executive order states:

“The lack of appropriate research on medical cannabis and consequent lack of FDA approval leaves American patients and doctors without adequate guidance on appropriate prescribing and utilization… It is the policy of my Administration to increase medical cannabis and CBD research to better inform patients and doctors.”

Universities, hospitals, and companies will soon be able to conduct federally sanctioned studies, opening the door to more robust clinical trials on therapeutic uses, dosage standards, and delivery mechanisms. This shift positions American institutions to lead research that has largely been conducted abroad due to prior restrictions.

Perhaps the most significant business impact is the end of Internal Revenue Code Section 280E’s application to cannabis operators. Cannabis businesses can now take standard deductions, improving profitability, providing long-sought financial relief, and aligning federal tax policy with the regulated cannabis market.

Armstrong Teasdale’s Cannabis Law practice constantly monitors issues and opportunities relevant to our clients. Contact your regular AT lawyer or one of the authors to discuss your particular situation.

Contact Us
  • Worldwide
  • Chicago, IL
  • Denver, CO
  • Edwardsville, IL
  • Jefferson City, MO
  • Kansas City, MO
  • Miami, FL
  • New York, NY
  • Philadelphia, PA
  • St. Louis, MO
  • Washington, D.C.
  • Wilmington, DE
Worldwide
abstract image of world map
Chicago, IL
100 North Riverside Plaza
Suite 1500
Chicago, IL 60606-1520
Google Maps
Chicago, Illinois
Denver, CO
4600 South Syracuse Street
Suite 1400
Denver, CO 80237
Google Maps
Denver, Colorado
Edwardsville, IL
115 N. Second St.
Edwardsville, IL 62025
Google Maps
Edwardsville, Illinois
Jefferson City, MO
101 E. High St.
First Floor
Jefferson City, MO 65101
Google Maps
Jefferson City, Missouri
Kansas City, MO
2345 Grand Blvd.
Suite 1500
Kansas City, MO 64108
Google Maps
Kansas City, Missouri
Miami, FL
355 Alhambra Circle
Suite 1200
Coral Gables, FL 33134
Google Maps
Photo of Miami, Florida
New York, NY
400 Park Ave.
12th Floor
New York, NY 10022
Google Maps
New York City skyline
Philadelphia, PA
2005 Market Street
29th Floor, One Commerce Square
Philadelphia, PA 19103
Google Maps
Philadelphia, Pennsylvania
St. Louis, MO
7700 Forsyth Blvd.
Suite 1800
St. Louis, MO 63105
Google Maps
St. Louis, Missouri
Washington, D.C.
1717 Pennsylvania Avenue NW
Suite 400
Washington, DC 20006
Google Maps
Photo of Washington, D.C. with the Capitol in the foreground and Washington Monument in the background.
Wilmington, DE
1007 North Market Street
Wilmington, DE 19801
Google Maps
Wilmington, Delaware